2,522 research outputs found

    Special educational needs, social care and health

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    Better understanding of the proportion of children who ever receive special educational needs (SEN) provision or social care services during school years is highly relevant for healthcare as reductions in one or more of these services could impact on healthcare. Using the National Pupil Database linked to the all-of-England children looked after return and children in need census, we estimated the cumulative incidence of SEN status among (1) children ever in care during school, (2) children in need but not care, and (3) neither. We observed a very high proportion of children who were in care or need during school years had SEN provision at some point (83% and 65%, respectively), and that a high proportion of children in neither of these groups did so, too (37%). Healthcare, SEN provision and social care services focus on a similar population of children. Better integration of these services could lead to synergies and cost-efficiencies and better support for these children and their families

    A Nonpolymorphic Class I Gene in the Murine Major Histocompatibility Complex

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    DNA sequence analysis of a class I gene (QlO), which maps to the Qa2,3 locus in the C57BL/lO (H- 2b haplotype) mouse, reveals that it is almost identical to a cDNA clone (pH16) isolated from a SWR/J (H-2q haplotype) mouse liver cDNA library. Exon 5, in particular, has an unusual structure such that a polypeptide product is unlikely to be anchored in the cell membrane. Our findings suggest that the two sequences are derived from allelic class I genes, which are nonpolymorphic, in contrast to H-2K allelic sequences from the same mice, and they may encode liver-specific polypeptides of unknown function. Our previous studies indicate that the QlO gene is a potential donor gene for the generation of mutations at the H-2K locus by inter-gene transfer of genetic information. Thus the lack of polymorphism in class I genes at the QlO locus implies either that they are not recipients for such exchanges or that selective pressure prevents the accumulation of mutations in genes at this locus

    Evaluation of high performance LMFBR blanket configurations

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    Substantially the same as a Ph. D. thesis by G.J. Brown in the Dept. of Nuclear Engineering, MIT, 1974Includes bibliographical references (pages 249-254)AEC Contract AT(11-1)-225

    Intrusion Signature Creation via Clustering Anomalies

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    Current practices for combating cyber attacks typically use Intrusion Detection Systems (IDSs) to detect and block multistage attacks. Because of the speed and impacts of new types of cyber attacks, current IDSs are limited in providing accurate detection while reliably adapting to new attacks. In signature-based IDS systems, this limitation is made apparent by the latency from day zero of an attack to the creation of an appropriate signature. This work hypothesizes that this latency can be shortened by creating signatures via anomaly-based algorithms. A hybrid supervised and unsupervised clustering algorithm is proposed for new signature creation. These new signatures created in real-time would take effect immediately, ideally detecting new attacks. This work first investigates a modified density-based clustering algorithm as an IDS, with its strengths and weaknesses identified. A signature creation algorithm leveraging the summarizing abilities of clustering is investigated. Lessons learned from the supervised signature creation are then leveraged for the development of unsupervised real-time signature classification. Automating signature creation and classification via clustering is demonstrated as satisfactory but with limitations

    Irrigation Management To Control Nitrate Leaching: What Is In It For The Framer?

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    Managing irrigation application is an important tool in controlling the amount of nitrate that leaches out of the root zone

    Managing to Reduce Nitrate Leaching: What is in it for the Farmer?

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    Nitrates leached into groundwater may be associated with the following: (1) methemoglobinemia (blue baby) in humans and other mammals; (2)cardiovascular collapse and shock in horses; (3) possibility of cancer (EPA); and (4) eutrophication of water bodies (IFIA) when nitrate contaminated groundwater reaches surface water through wells or springs. Nitrate leaching is not only a possible source of environmental damage but also the loss of an input before it is used in production

    Nitrogen Source and Application Method: Does It Matter?

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    Irrigation management has a greater effect on the amount of nitrate that is leached out of the root one than does the type of nitrogen applied

    Superoperator Analysis of Entanglement in a Four-Qubit Cluster State

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    In this paper we utilize superoperator formalism to explore the entanglement evolution of four-qubit cluster states in a number of decohering environments. A four-qubit cluster state is a resource for the performance of an arbitrary single logical qubit rotation via measurement based cluster state quantum computation. We are specifically interested in the relationship between entanglement evolution and the fidelity with which the arbitrary single logical qubit rotation can be implemented in the presence of decoherence as this will have important experimental ramifications. We also note the exhibition of entanglement sudden death (ESD) and ask how severely its onset affects the utilization of the cluster state as a means of implementing an arbitrary single logical qubit rotation.Comment: 9 pages, 9 composite figures, presentation of results completely rewritte

    Berle VIII: Benefit Corporations and the Firm Commitment Universe

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    Benefit corporation law is a critical tool to allow private capital to be invested in a manner that creates shared and durable value for everyone. But a tool is only as good as the person who uses it. As highlighted in Rick Alexander’s essay, shareholders must understand the value of firm commitment, and, more importantly, the ultimate source of wealth for universal investors, which is thriving financial markets and a healthy, peaceful, and prosperous planet. These goals can only be attained and maintained for the long term if private capital is allocated and invested in a manner that creates value for everyone. So investors must learn to use benefit corporation law as a tool to require the companies they own to create value in a responsible and sustainable manner

    Data Resource: The National Pupil Database (NPD)

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    Introduction: The National Pupil Database (NPD) is a record-level administrative data resource curated by the UK government's Department for Education that is used for funding purposes, school performance tables, policy making, and research. Processes Data are sourced from schools, exam awarding bodies, and local authorities who collect data on an on-going basis and submit to the Department for Education either termly or yearly. Data contents NPD contains child-level and school-level data on all pupils in state schools in England (6.6 million in the 2016/17 academic year). The primary module is the census, which has information on characteristics and school enrolment. Other modules include alternative provision, exam attainment, absence and exclusions. Data from children's social care are also available on children referred for support and those who become looked after. Children's records are linkable across different modules and across time using a nationally unique, anonymised child-level identifier. Linkage to external datasets has also been accomplished using child-level identifiers. Conclusions The NPD is an especially valuable data resource for researchers interested in the educational experience and outcomes of children and young people in England. Although limited by the fact that children in private schools or who are home schooled are not included, it provides a near-complete picture of school trajectories and outcomes for the majority of children. Linkage to other datasets can enhance analyses and provide answers to questions that would otherwise be costly, time consuming and difficult to find
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